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Ageratum conyzoides L, (Asteraceae), is an annual herbaceous plant with a long history of traditional medicinal uses in several countries of the world and also reputed to possess varied medicinal properties. This present study was undertaken to investigate the antidotal properties of leaf extracts of Ageratum conyzoides. A part of the dried pulverized leaves was extracted with methanol to obtain the crude extract. Another part was successively extracted with n-hexane, ethylacetate and methanol to yield the respective fractions.