By Ogbu, K.i.; Anene, B.m.; Nweze, N.e.; Chukwudi, I.c.; Eze, U.u.; Chinyere, C.n.; Pam, V.a.
Clinico-haematological effects of single and mixed experimental infection of Trypanosoma congolense and Trypanosoma brucei on parvoviral vaccinated dogs were studied in mongrel dogs. Twenty dogs of mixed sexes and 4-6 months of age weighing an average of 6.3 kg were used for the experiment. The dogs were divided into five groups of four animals each. Group A were vaccinated and uninfected, group B were unvaccinated and uninfected, group C were vaccinated and infected with T. congolense, group D were vaccinated and infected with T. brucei and group E were vaccinated and infected with T. congolense and T. brucei. Clinical signs observed in the dogs were pyrexia, anorexia, emaciation, lethargy, rough hair coat, white ocular discharges and pale mucus membranes. Trypanosoma brucei and T. congolense had pre-patent period of 6 and 21 days respectively post infection while that of the mixed infection was 7 days post infection when T. brucei became evident. Although the clinical signs of infection due to both species were generally similar, pyrexia appeared to be more characteristic of T. brucei than of T. congolense infection. Significant decrease (P