By Udegbunam, Rita Ijeoma, Udegbunam, Sunday Ositadimma, Onuba, Austine Chukwudum, Ugwu, Nnenna Ebere
The effect of pentazocine on diazepam/ketamine anaesthesia was evaluated in this
study. Pentazocine (10 mg/kg) was administered intramuscularly (im) prior to injection
of diazepam (2 mg/kg, iv) and ketamine (15 mg/kg, im) in pentazocine
/diazepam/ketamine (P/D/K) group. In the diazepam/ketamine group, anaesthesia was
induced using diazepam (2 mg/kg, iv) and ketamine (15 mg/kg, im). All rabbits were
laparotomized after induction of anaesthesia. Intra operatively, anaesthetic indices,
physiologic variables and pain responses of rabbits were studied. Blood glucose and
serum cortisol of rabbits were monitored post laparotomy. The durations of analgesia and
anaesthesia were significantly shorter (p